Table of contents
- Composition and shape of an issue
- Pharmacological properties
- Undesirable consequence
- Reception and dosage
- Interaction with other medications
- Application features
Lyrica is an antiepileptic agent that helps to ease the condition in case of neuropathic pains, fibromyalgia and to relieve the anxious condition. It fights depression and anxiety but can be addictive.
Pregabalin (25mg 75mg 150mg) Review Side Effects Anxiety and Withdrawal : video
Lyrica : Composition and shape of an issue
Available in gelatin capsules marked on the housing depending on the dosage. Manufacturer Pfizer Germany.
The main active component is pregabalin in the dosage of 0.025, 0.075, 0.15, 0.3 gr. and auxiliary components. In aluminum blister 10, 14, or 21 pieces. In a pack of cardboard 1 or 4 blister packs of 14 pcs., 4 blister packs of 21 pcs. or 10 blister packs of 10 pcs.
The capsules contain white powder.
Lyrica (Pregabalin) is similar in its action to the main inhibitory neurotransmitter of the central nervous system - γ-amino oil acid (GABA). The drug is characterized by rapid action, is endowed with analgesic and ataractic effect, ie selectively suppresses anxiety, fear, and anxiety, increased emotional excitement, as well as reduces the frequency of involuntary muscle crush.
In the treatment of patients with polyneuropathy against the background of diabetes and neuralgia, which developed as a complication of herpes zoster, notes improvement after the first week of treatment. The effect of the therapy is maintained for a month, the pain is reduced by 50% on average.
In diffuse generalized skeletal-muscular pain, there is a marked decrease. Also, patients have increased physical activity and reduced sleep disturbance.
In epileptic seizures, the frequency of seizures decreases as early as 7 days from the beginning of the admission.
In the case of anxiety disorders, an improvement is observed already in the first week of treatment.
It is excreted mainly through the urinary system in an unchanged form. It has rapid absorption, especially on an empty stomach. The maximum plasma content is reached 60 minutes after use and does not depend on the frequency of administration. The use of the drug after a meal reduces its concentration and increases the absorption period to 150 minutes.
Lyrica is prescribed for a patient with epileptic activity, which is characterized by short-term involuntary muscle contractions regardless of the body part.
The drug also shows high effectiveness in neuropathic pain, which is a consequence of damage to the peripheral or Central nervous system.
Pregabalin is also effective for generalized pain, including severe severity, which develops against the background of fibromyalgia.
The tool perfectly removes the manifestations of anxiety in adults.
The main contraindications are:
- hypersensitivity to the components;
- hereditary diseases associated with malabsorption and lactose tolerance;
- children under 18 years of age.
With great care, Lyrica is prescribed for kidney and heart failure. Due to reported cases of uncontrolled use, it is not advisable to prescribe the drug to people with drug dependence, as it can cause the development of drug dependence.
Against the background of treatment with this drug, all patients should be under close and continuous medical supervision.
Use during gestation and breast-feeding
Against the background of Lyrica treatment, it is not advisable to feed the baby with breast milk. During pregnancy, the drug may be prescribed if the intended benefit to the mother exceeds the possible risks to the fetus by several times.
Often, against the background of treatment, dizziness and hypersomnia are observed, which are expressed in light or moderate severity.
The main undesirable consequences that lead to the cancellation of the drug include impaired coordination of movements in the absence of muscle weakness, confusion, neuropsychiatric weakness, changes in concentration, visual acuity, discoordination, and peripheral edema.
Various allergic reactions can also occur, ranging from urticaria to anaphylactic shock.
Against the background of treatment, nasopharyngitis may develop, impaired clarity and visual acuity, hyperemia of the shell, and eye edema.
The drug can increase the feeling of thirst and hunger, or, conversely, bring patients to anorexia.
The main component can reduce the content of neutrophils in the plasma, which leads to an increase in heart rate, causes a slowdown in the heart rate and sinus arrhythmia.
Against the background of treatment with pregabalin, coordination disorders, and loss of orientation in space and time, memory difficulties, weakness, lethargy, and deterioration of General health, increased nervousness and a depressive mood are possible.
From the bronchopulmonary system, the following manifestations may be observed: shortness of breath, cough, nosebleeds, hiccups, and pulmonary edema.
Pregabalin can negatively affect sleep, cause headaches, convulsions, paranoid mood, inflammatory lesions of the brain membranes, and most importantly provoke dependence (therefore, its use should be canceled gradually, otherwise it can cause withdrawal syndrome).
Nausea, gag reflex, flatulence, constipation or diarrhea, pancreatitis, cholecystitis can also be provoked by this tool.
On the skin side, bedsores, ulcers, rashes, irreversible changes in the form of a decrease in the number of elastic fibers can be observed.
In men, there may be a violation of erectile function, swelling of the mammary glands in the female half – a violation of the menstruation cycle.
The medication can increase blood sugar and lower potassium levels.
It can also cause joint swelling, muscle spasms and pain, kidney function disorders, cause incontinence, and the presence of blood in the urine.
Reception and dosage
Daily dosage of the Lyrica varies from 150 to 600 mg., which should be divided into 2-3 doses, regardless of food.
As a rule, initially, the dosage does not exceed 150 mg, and with good drug tolerance, it is increased from the dose that is necessary for the complete removal of symptoms. The specific dosage is selected strictly individually and directly depends on the severity of the disease and the severity of symptoms.
The medication is withdrawn gradually, but not less than 7 days. With the abrupt withdrawal, it is possible to develop an abstinent syndrome, which resembles the withdrawal syndrome in drug-dependent people, which manifests as insomnia, headache, nausea, stool disorders, flu-like conditions, mental disorders, increased sweating, dizziness, convulsive activity, and anxiety. The dosage and duration of treatment with the medication do not affect the treatment.
If the prescribed dose does not exceed 0.15 g. signs of overdose are not observed. At a dose higher than 0.6 g. per day, an overdose may develop, which manifests itself in the form of increased excitability, anxiety, or the complete opposite effect: sharp drowsiness and confusion.
All treatment measures are aimed at relieving symptoms of overdose. To do this, gastric lavage is performed, symptomatic treatment is performed, and if necessary, an artificial kidney device is connected.
Interaction with other medications
Lyrica may increase the effects of ethyl alcohol and lorazepam. You should not prescribe Lyrica against the background of therapy with medications that depress the Central nervous system since this is fraught with the development of a comatose state and respiratory arrest.
Simultaneous administration with medications that cause defecation and constipation, especially with non-narcotic analgesics, is not desirable.
The medication may increase the mental and motor disorders that are caused by oxycodone.
The drug is not prescribed to people with lactose intolerance and children under 18 years of age.
People with diabetes may have weight gain.
It is necessary to stop taking the medication if the patient develops edema of the face or extremities.
During Lyrica therapy, you should not drive a vehicle. Also, do not work with mechanisms that, if not used correctly, can cause harm to health and life-threatening, since the medication can cause dizziness and hypersomnia.
Elderly people can be prescribed medication, but the dosage should be reduced since they already tend to have impaired normal kidney function.
In a situation where you have missed the next dose of medication, you should take the next dose as soon as possible, but do not use the missed dose if the time of the next intake is appropriate.
Vacation in a pharmacy chain
The Pregabalin is a prescription drug, but in our drugstore you can only buy Lyrica without a prescription (after a doctor's consultation).
Summing up, we can say that the Lyrica show good results if it is taken as prescribed by a specialist and for medicinal purposes. However, the drug strongly affects the mental state of the patient, so taking it for non-medical purposes is fraught with serious consequences, and in particular, the development of addiction, which is not much different from the drug. According to statistics, there are many cases when uncontrolled intake led to tragic consequences. But, due to the lack of facts, it is impossible to say with certainty that the drug leads to the development of persistent addiction and causes irreparable harm to health.